Important

It is possible that the main title of the report Laband Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

Zimmermann-Laband Syndrome
Gingival Fibromatosis, Abnormal Fingers, Nails, Nose, Ear, Splenomegaly
ZLS

Disorder Subdivisions

None

General Discussion

Laband Syndrome is an extremely rare inherited disorder characterized by abnormalities of the head and facial (craniofacial) area and the hands and feet. Most children with this disorder have abnormally large gums (gingival fibromatosis). Overgrown gums may affect the ability to chew, swallow, and/or speak. In addition, affected infants may exhibit abnormally long, thin fingers and toes and/or deformed (dysplastic) or absent nails at birth. In some cases, mental retardation may also be present. Laband Syndrome is inherited as an autosomal dominant trait.