Important

It is possible that the main title of the report Bartter's Syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synoyms

• Aldosteronism With Normal blood pressure
• Hyperaldosteronism With Hypokalemic Alkatosis
• Hyperaldosteronism Without Hypertension
• Juxtaglomerular Hyperplasia
• Hypokalemic Alkalosis with Hypercalciuria

Disorder Subdivision

None

General Discussion

Bartter's Syndrome, also known as is hypokalemic alkalosis with hypercalciuria, is a rare inherited disorder characterized by growth deficiency, potentially resulting in short stature; muscle weakness; cramps; and/or loss of potassium from the kidneys (renal potassium wasting). In some cases, affected individuals may exhibit mental retardation. Individuals with Bartter's Syndrome have a disturbance in their acid-base ratio (i.e., an accumulation of base or loss of acid) associated with a loss of potassium (hypokalemic alkalosis). Low amounts of potassium may result from overproduction of a certain hormone (aldosterone) that is essential in controlling blood pressure and regulating sodium and potassium levels (hyperaldosteronism). The exact cause of Bartter's Syndrome is not known; in some cases, it may be inherited as an autosomal recessive genetic trait.